|50mg/ml||10ml vial /box|
|MK 677 is a potent, long-acting, orally-active, selective, and non-peptide agonist of the ghrelin receptor and a growth hormone secretagogue, mimicking the growth hormone (GH)-stimulating action of the endogenous hormone ghrelin. It has been shown to increase the secretion of several hormones including GH and insulin-like growth factor 1 (IGF-1) and produces sustained increases in the plasma levels of these hormones without affecting cortisol levels.|
MK-677, (HCl salt)
|MeSH Entry Terms|
|Chemical and physical data|
|Molecular Weight||528.67 g·mol−1|
|Boiling point||868.9 °c at 760 mmhg|
|Enthalpy of Vaporization|
|Index of Refraction||1.632|
|Molar Refractivity||142.7±0.4 cm3|
|Solubility||DMSO (Slightly), Methanol (Slightly), Water (Slightly)|
|Polar Surface Area||130 Å2|
|Surface Tension||63.5±5.0 dyne/cm|
|Molar Volume||400.1±5.0 cm3|
|CAS Number||159634-47-6 / 159752-10-0|
|DSSTox Substance ID||DTXSID90166700|
|Smiles||O=S(C)(=O)N(C2)c1ccc cc1C23CCN(CC3 )C(=O)C(NC(=O)C(N) (C)C)COCc4ccc cc4|
|Canonical SMILES||CC(C)(C(=O)NC(C OCC1=CC=CC=C1)C(=O) N2CCC3(CC2)CN(C4=CC =CC=C34)S(=O)(=O)C)N|
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